Chronic renal transplant rejection
Chronic renal transplant rejection is a form of renal transplant rejection. It usually later following transplantation.
Pathology
Chronic rejection is defined as a gradual deterioration in graft function beginning at least 3 months after transplantation .
The creatinine levels may rise but this does not allow differentiation from acute transplant rejection.
Histological diagnosis is made a demonstration of graft arteries and arteriolar proliferation, interstitial cellular infiltration and fibrosis, tubular atrophy, and glomerular changes.
Risk factors
- previous episodes of acute rejection
Radiographic features
Ultrasound
Imaging of choice. features include
- mild dilatation of the collecting system: may occasionally be seen in cases of chronic rejection.
- the cortex may be thin
- narrowing at the ureterovesical junction
- focal pyelonephritis
- elevated renal arterial resistive indices
See also
