Histiocytic sarcoma
Histiocytic sarcoma is a rare malignant hematopoietic neoplasm that has been reported in association with other hematological malignancies (particularly B and T cell lymphomas).
Pathology
It comprises of tumor cells derived from the monocyte/macrophage lineage.
Location
It usually occurs in lymph nodes, skin, and the gastrointestinal tract. Occurrence in the CNS system has also been rarely reported.
Prognosis
The overall prognosis is generally poor due to rapid progression and poor response to therapy. Tumor size may be a prognostic factor.
History and etymology
It was first described by Mathé et al. in 1970.
See also
