Chronic pulmonary aspergillosis

Chronic pulmonary aspergillosis (CPA) is a group of chronic aspergillosis found in non-immunocompromised patients with prior or current lung disease (e.g. chronic obstructive pulmonary disease, mycobacteriosis or conditions such as diabetes).

It can manifest as several forms.

• chronic cavitary pulmonary aspergillosis (CCPA): considered the most common form.
• chronic necrotizing pulmonary aspergillosis (CNPA)
• chronic fibrosing pulmonary aspergillosis (CFPA): may progress to this from CCPA in untreated cases
• Aspergillus nodule
• aspergilloma

Clinical presentation

Patients usually present with chronic symptoms such as prolonged and relapsing cough, dyspnea and weight loss. Acute symptoms such as hemoptysis and bronchial or pulmonary hemorrhage may however occasionally occur .​