Vitamin B6 deficiency

Vitamin B6 deficiency (also known as hypovitaminosis B6) is rare, as the B6 vitamers are present in many commonly-consumed foodstuffs. It is most commonly seen in the context of chronic ethanol excess, although many other risk factors are known. In children, deficiency may manifest as seizures. But in adults marked hypovitaminosis B6 more usually presents with altered mentation and skin rashes. Other manifestations might include a normocytic anemia, angular cheilitis, and glossitis. A depressive illness may be a feature. The deficiency usually shows a good response to oral/IV administration of pyridoxine.