2014 WHO classification of endometrial stromal tumors

The 2014 WHO classification is one of the classification systems for endometrial stromal tumors (EST).

Endometrial stromal tumors constitute <2% of all uterine tumors and <10% of uterine mesenchymal neoplasms .

Over the past four decades, EST classification has gone through various modifications, starting from the earliest study by Norris and Taylor . This was primarily due to the rarity of the tumors. With better understanding, and at the time of writing (mid-2016), the 2014 WHO classification has replaced the broad categories of the 2003 WHO classification following incorporation of molecular findings.

Classification

  • endometrial stromal nodule (ESN)
  • low-grade endometrial stromal sarcoma (LGESS)
  • high-grade endometrial stromal sarcoma (HGESS)
  • undifferentiated uterine sarcoma (UUS)
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