Abrodil
Abrodil (marketed as Skiodan in the US) was a water-based iodinated contrast medium introduced for clinical use in 1930 . It was developed by Bronner, Hecht and Schueller in Germany. Chemically, Abrodil is the sodium salt of monoiodomethanesulfonic acid.
It was initially employed for intravenous pyelography, but it became popular for myelography and first tried in 1931. It was commonly employed in Scandinavia but never gained traction elsewhere, primarily due to its associated headache, ocular pain and leptomeningeal irritation.