agenesis of the internal carotid artery

Agenesis of

internal carotid artery associated with isolated growth hormone deficiency: a case report and literature review. A MRI angiography time-of-flight (TOF) three-dimensional (3D) technique through the circle of Willis revealed agenesis of the intracranial portion of the left internal carotid artery (ICA). a. 3D TOF in the axial plane at the carotid siphon level shows agenesis of the left ICA. b. 3D TOF in the axial plane for the vertebrobasilar system shows the left vertebral artery and the compensatory hypertrophy. c. MRI angiography maximum intensity projection (MIP) reconstruction in the axial plane reveals agenesis of the intracranial portion of the left ICA. d. MRI angiography MIP reconstruction in the coronal plane highlights hypertrophy in the left vertebral collateral blood flow. e. Sagittal T1W TSE sequence shows adenohypophyseal hypoplasia (height 2.5 mm and width 3.5 mm) with a lack of posterior pituitary hyperintensity

Stroke in

sickle cell disease in association with bilateral absence of the internal carotid arteries. Case report. MR images axial T2W (A), sagittal FLAIR (B), axial DWI&ADC (C&D) revealed territories in the right frontal and both parietal lobes involved with acute watershed infarcts. Abbreviations: FLAIR- Fluid-attenuated inversion recovery, DWI diffusion-weighted imaging, ADC apparent diffusion coefficient map

Stroke in

sickle cell disease in association with bilateral absence of the internal carotid arteries. Case report. MRA-3D TOF showed no visible flow in both internal carotid arteries with reperfusion of anterior circulation through the prominent posterior circulation including basilar (arrows) and “posterior cerebral arteries” (asterisks).Abbreviations: TOF MRA - time of flight MR angiography

Stroke in

sickle cell disease in association with bilateral absence of the internal carotid arteries. Case report. Brain arteries with corresponding almost equal segments look like “normal” circle of Willis; Anterior circulation is supplied through the prominent posterior circulation including dominant basilar (arrows) and posterior communicating arteries (asterisks) presenting on axial MIP CTA (A) and also on reformatting coronal MIP CTA images (B, C,). Abbreviations: CTA- Computed Tomography Angiography; MIP- maximum intensity projection

Stroke in

sickle cell disease in association with bilateral absence of the internal carotid arteries. Case report. The complete absence of all segments of the internal carotid arteries on either side has shown in VR (A) and dominant vertebral arteries (B) while slim gracile common carotid arteries presented on coronal MIP CTA image (C)

Stroke in

sickle cell disease in association with bilateral absence of the internal carotid arteries. Case report. Absence of bony carotid canals in petrous bones detecting with bone window axial (A) and coronal (B and C) CT images, confirming the finding of agenesis both ICA