Albright hereditary osteodystrophy

Albright hereditary osteodystrophy (AHO) is a form of osteodystrophy and is also classified as a phenotype of pseudohypoparathyroidism (i.e. type 1a).

Typical clinical spectrum includes

• short, stocky build
• round facies with a low, flat nasal bridge
• short neck
• ectopic ossifications
• brachymetaphalangism
• developmental delay, with or without endocrine abnormalities .

There can be considerable phenotypic variation between patients.

History and etymology

It is named after Dr Fuller Albright (American endocrinologist) who first characterized it in 1942.

Siehe auch:

• Osteodystrophy

und weiter:

• Akrodysostose