Albright-Osteodystrophie

Albright hereditary osteodystrophy (AHO) is a form of osteodystrophy and is also classified as a phenotype of pseudohypoparathyroidism (i.e. type 1a).

Typical clinical spectrum includes

  • short, stocky build
  • round facies with a low, flat nasal bridge
  • short neck
  • ectopic ossifications
  • brachymetaphalangism
  • developmental delay, with or without endocrine abnormalities .

There can be considerable phenotypic variation between patients.

History and etymology

It is named after Dr Fuller Albright (American endocrinologist) who first characterized it in 1942.

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