Amyoplasia congenita is a syndrome characterized by multiple specific congenital joint contractures, associated with substitution of muscular tissue by fibrosis and adipose tissue.
The estimated incidence is at 1: 10000 live births. There may be a higher prevalence with twin pregnancies.
The muscles are hypoplastic and replaced by a mixture of fat and fibrosis
It is throught to occur sporadically
The term a-myo-plasia essentially derives from the Latin meaning no-muscle-development