Anaplastic large cell lymphoma

Anaplastic large cell lymphoma (ALCL) is a form of hematological malignancy. It as first described in 1985 as a large-cell neoplasm with anaplastic morphology immunostained by the Ki-1 antibody, which recognizes CD30.

There are two main sub types

• anaplastic large-cell lymphoma, ALK-positive
• anaplastic large-cell lymphoma, ALK-negative

See also

• anaplastic lymphoma kinase (ALK) gene rearrangements
• WHO classification of tumors of hematopoietic and lymphoid tissues