Androgen deprivation therapy (ADT)
Androgen deprivation therapy (ADT), also called androgen suppression therapy or is a form of treatment in prostate cancer, which basically aims to slow prostate cancer growth by blocking the effect of androgens e.g. testosterone.
Such therapy is mainly used for treating men with intermediate- and high-risk localized prostate cancer in combination with radiotherapy .
Effects on imaging:
mpMRI
shrinkage of prostate volume
loss of T2 signal
increase of ADC values in prostate cancer
decrease of ADC values of benign prostatic tissue
reduced DCE of prostate cancer
PET/CT
reduced visibility of hormone-sensitive prostate cancer in PSMA PET/CT