Clear cell ependymoma

Clear cell ependymomas are a histological variant of ependymoma characterized by prominent perinuclear cytoplasmic clearing, reminiscent of oligodendrogliomas .

They are typically encountered in younger patients and usually in the supratentorial compartment .

They have a tendency to be quite vascular and may have a worse prognosis . RELA fusion-positive ependymomas are not infrequently of clear cell morphology .