Clinically unclassifiable parkinsonism

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Clinically unclassifiable parkinsonism (CUP) is a term applied to patients who have some parkinsonism features, but who do not fulfill clinical criteria for a particular disorder such as:

Some measures have been investigated and found to be useful in predicting evolution from CUP to PSP, e.g. Magnetic Resonance Parkinsonism Index (MRPI) or midbrain to pons area ratio.