Congenital limb amputation
Congenital limb amputation is the absence of a fetal limb or part of a limb that usually occurs due to disruption of vascular supply.
Epidemiology
Congenital amputations occur in 0.5 (range 0.03-1) per 1000 live births .
Pathology
They are slightly more common in the upper limb (60%) than in the lower limb (40%) .
Etiology
- amniotic band syndrome (most common )
- amniotic adhesion
- resorptive necrosis due to limb movement restriction in oligohydramnios
- vasoactive teratogens
Differential diagnosis
