focal cortical dysplasia of Taylor

Focal
cortical dysplasia. Asymmetry in the gyral pattern in both frontal lobes with increased cortical thickness of left frontal lobe. Slight blurring of Grey-white matter junction.
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Focal
cortical dysplasia. Sulci appear abnormally deep with increased cortical thickness in left frontal lobe.
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Focal
cortical dysplasia. Sulci appear abnormally deep with increased cortical thickness in left frontal lobe.
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Focal
cortical dysplasia. T2W oblique coronal image showing increased focal cortical thickness of left frontal lobe.
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Focal
cortical dysplasia. FLAIR oblique coronal image showing focal increased cortical thickness in left frontal lobe.
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Classification
system for malformations of cortical development • Focal cortical dysplasia - Ganzer Fall bei Radiopaedia
Gaillard, F. Focal cortical dysplasia. Case study, Radiopaedia.org. (accessed on 08 Nov 2022) https://doi.org/10.53347/rID-5561 • CC by-nc-sa 3.0 (modified)
Radiopaedia • CC-by-nc-sa 3.0 • de

Taylor dysplasia is a type of focal cortical dysplasia and a common cause of refractory epilepsy. Under both the Palmini classification and the more recent Blumcke classification of focal cortical dysplasia, Taylor dysplasia is classified as type II.

For further discussion of the radiographic features please refer to the parent article: focal cortical dysplasia.

Pathology

Taylor dysplasia is determined histologically due to the presence of certain features such as  giant neurons, dysmorphic neurons with or without balloon cells . The latter further divides FCDT into two main subtypes .

  • type IIa: no balloon cells
  • type IIb: balloon cells present

See: Palmini classification and Blumcke classification.

History and etymology

Taylor dysplasia is named after David C. Taylor, a British psychiatrist who first described it in 1971 .

Siehe auch:
und weiter:
Assoziationen und Differentialdiagnosen zu Taylor type cortical dysplasia:
Fokale
kortikale Dysplasie
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