giant fibroadenoma

Giant
juvenile fibroadenoma in an 11-year-old girl.. Our patient"s photograph illustrated a lump in the left breast with prominent veins on the skin (head arrow).
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Giant
juvenile fibroadenoma in an 11-year-old girl.. PA chest X-ray showed a mass in the left breast (asterisk) without evidence of bone involvement, pulmonary nodules or pleural effusion.
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Giant
juvenile fibroadenoma in an 11-year-old girl.. Ultrasound demonstrated a hypoechoic, well-defined mass replacing most of the normal left breast tissue. It measured 11.3x10.5 cm (APxT).
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Giant
juvenile fibroadenoma in an 11-year-old girl.. The mass is avascular during colour Doppler evaluation.
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Giant
juvenile fibroadenoma in an 11-year-old girl.. MRI demonstrated a well-defined mass that was predominantly isointense in T1-weighted images.
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Giant
juvenile fibroadenoma in an 11-year-old girl.. STIR-T2 sequence showed a hyperintense left breast mass (asterisk) that replaced the normal breast tissue towards the tail of the breast (white arrow).
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Giant
juvenile fibroadenoma in an 11-year-old girl.. The mass replaced most of the normal breast tissue in this 3D- MIP MRI reconstruction (asterisk).
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Giant fibroadenomas are fibroadenomas weighing more than 500 grams or measuring >5 cm in size.

Please refer to fibroadenoma article for further details.

Epidemiology

They are usually encountered in pregnant or lactating women.

Clinical presentation

The typical presentation is in a woman with a large palpable breast lump.

Pathology

Microscopically both stromal and epithelial cells.

Radiographic features

Radiographic features are the same of normal fibroadenomas.

Mammography

Variable features from the well-circumscribed discrete oval mass hypo- or isodense to the breast glandular tissue, to a mass with macrolobulation or partially obscured margin. Involuting lesions can produce classic, coarse popcorn calcification appearance.

Ultrasound

Well-circumscribed, round and/or macrolobulated mass with homogenous hypoechogenicity.

MRI
Signal characteristics
  • T1: mostly hypointense or isointense 
  • T2: variable intensity
  • T1 C+ (Gd): variable

Treatment and prognosis

Although benign, giant fibroadenomas should be excised because of their similar clinicoradiological presentation to the malignant phyllodes tumor.

Siehe auch:
Assoziationen und Differentialdiagnosen zu Riesenfibroadenom der Mamma:
Fibroadenom
 
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juveniles
Fibroadenom der Mamma
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