Hand-foot syndrome (chemotherapy)
Hand-foot syndrome, also known as palmar-plantar erythrodysaesthesia or Burgdorf reaction, is a benign, aseptic, self-limiting complication of many chemotherapeutic agents characterized by a widespread erythema, edema and ulceration of the hands and feet.
Causative drugs
Many chemotherapeutic agents have been described as causing hand-foot syndrome including :
- 5-fluorouracil
- capecitabine
- cyclophosphamide
- cytarabine
- docetaxel
- etoposide
- hydroxyurea
- liposomal doxorubicin
- mercaptopurine
- methotrexate
- paclitaxel
- sorafenib
- sunitinib
- tegafur
- vinorelbine
Disambiguation
Hand-foot syndrome in the setting of chemotherapy should not be confused with:
