infarct core
The infarct core denotes the part of an acute ischemic stroke which has already infarcted, or is irrevocably destined to infarct regardless of reperfusion. It is also referred to as established infarct and is in distinction from the penumbra which remains potentially salvageable.
CT perfusion
On CT perfusion the infarct core is defined as the area of the brain with :
By contrast, the ischemic penumbra will have only moderately decreased cerebral blood flow and normal or even increased cerebral blood volume due to autoregulation.
MRI
On MRI, the infarct core correlates closely with restricted diffusion on diffusion-weighted imaging .