Light chain deposition disease (pulmonary manifestations)

Pulmonary manifestations of light chain deposition disease are rare when considering the full disease spectrum of light chain deposition disease.

Pathology

The light chains are secreted by a plasma clone and deposit in the alveolar walls, small airways, and vessels.

Radiographic features

CT

HRCT manifestations most commonly include nodules, lymphadenopathy, and cysts. Cyst formation is believed to correspond to dilation of the small airways .