malignes Zystosarkoma phylloides

Malignant
phyllodes tumor of the breast with rapid progression: a case report. Computed tomography showed a 20 cm heterogeneous mass in the right breast and axillary and supraclavicular lymph nodes swelling (arrow)
surgicalcasereports.springeropen.com • CC-by-4.0
Malignant
phyllodes tumor of the breast with rapid progression: a case report. Computed tomography revealed regrowth of tumor in the right chest, right lung and right pleural effusion
surgicalcasereports.springeropen.com • CC-by-4.0
Malignant
phyllodes tumor of the breast with rapid progression: a case report. Computed tomography showed a mild reduction in chest wall tumor and pleural dissemination after one cycle of AI therapy
surgicalcasereports.springeropen.com • CC-by-4.0
Malignant
phyllodes tumor of the breast with rapid progression: a case report. Computed tomography showed a rapid increase in right chest wall tumors and pleural dissemination
surgicalcasereports.springeropen.com • CC-by-4.0
Granulocyte-colony
stimulating factor-producing malignant phyllodes tumor of the breast: a rare case. Contrast-enhanced magnetic resonance imaging revealing a large lobulated mass. No apparent infiltration to the pectoral major muscle can be observed
surgicalcasereports.springeropen.com • CC-by-4.0
Granulocyte-colony
stimulating factor-producing malignant phyllodes tumor of the breast: a rare case. Fluorodeoxyglucose (FDG) positron emission tomography–computed tomography (PET–CT) of the left breast. a PET–CT reveals no distant metastasis, although mild-to-moderate homogeneity is seen. b FDG uptake is detected in the spine, pelvic bone, and long bones, suggesting bone marrow hyperactivity
surgicalcasereports.springeropen.com • CC-by-4.0
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Malignant phyllodes tumor of the breast accounts for up to a quarter of the phyllodes tumors.

Please, refer to the main article on phyllodes tumors for a general discussion.

Pathology

It is generally thought that it is the stromal component that becomes malignant . This may account for their haematogenous metastatic pattern.

Radiographic features

A substantial overlap in the imaging characteristics has been reported between benign and malignant phyllodes tumors. A tumor diameter of 3 cm or greater has been generally reported to be associated with a higher likelihood of malignancy .

Treatment and prognosis

Fewer than 20% of the malignant tumors metastasize. When metastatic disease does occur, the metastases usually spread haematogenously to the lungs, pleura, or bone. Surgery is the mainstay of treatment as they are not proven to be sensitive to radiotherapy or chemotherapy. Because lymphatic metastasis is rare, axillary nodal surgery is not indicated.

Siehe auch:
Assoziationen und Differentialdiagnosen zu maligner Phylloidestumor:
Mammakarzinom
 
Wikipedia • CC BY-SA 3.0
Phylloidestumor
 
Wikipedia • CC BY-SA 3.0