Metastasen medulläres Nierenkarzinom

Predictive

role of PD-L1 expression in the response of renal Medullary carcinoma to PD-1 inhibition. Axial CT demonstrating interval improvement in the metastatic lung lesions in patient 1 after 5 cycles of Nivolumab. a Left lower lobe nodule #1 prior to Nivolumab. b Left lower lobe nodule #1 after Nivolumab. c Left lower lobe nodule #2 prior to Nivolumab. d Left lower lobe nodule #2 after Nivolumab

Predictive

role of PD-L1 expression in the response of renal Medullary carcinoma to PD-1 inhibition. PET scan of patient 1 demonstrating disease progression. a Scan obtained in October 2016 showing prominent mediastinal lesions. b Latest scan in February 2017 after 28 cycles of nivolumab and palliative radiation to the mediastinum showing new metastatic lesions in the liver and lungs but resolution of medistanial disease