multilocular cystadenoma of prostate

Prostatic cystadenoma or multilocular cystadenoma of prostate is a rare benign neoplasm arising in the prostate gland.

If lesions are considerably large they may also be termed giant multilocular cystadenomas of the prostate.

Pathology

Lesions are histologically characterized by glands and cysts lined with cuboidal epithelium in a hypocellular fibrous stroma. Positive immunohistochemical staining of epithelial cells for PSA often confirm their prostatic origins. Macroscopically, the lesions are generally well circumscribed.

Radiographic features

Ultrasound/transrectal ultrasound (TRUS)

May show a large multiseptated cystic mass +/- some soft-tissue components may be present.

Treatment and prognosis

The natural history of prostatic cystadenomas are not well known, and there may be varying opinions on optimum management strategies. Although they are benign lesions, cystadenomas can be locally aggressive and be adherent to surrounding viscera.

Differential diagnosis

Imaging differential considerations include:

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