multiple myeloma of the skull

Radiological

review of skull lesions. Multiple myeloma. Skull radiograph (a), axial (b) and sagittal (c) head CT show multiple “punched out” lytic lesions in the calvarium (arrows), “salt and pepper” appearance

Imaging of

skull vault tumors in adults. Myeloma and plasmacytoma. Upper row. Myeloma. X-ray (a) NECT (b, c) and T1WI (d). Multiple “punched-out” lytic lesions with variable soft tissue components (a–c). Mandibular lesion suggesting myeloma instead of metastases (arrow in d). Note also the clival lesion (dashed arrow in d). Lower row. Plasmacytoma. NECT (e), T1WI post-contrast (f), and DSC-PWI (g). Single purely lytic transdiploic lesion with narrow zone of transition (arrows in e), hyperdense, hyperenhancing, and hypervascular (arrowheads respectively in e–g)