Pemtrexed induced pneumonitis

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Pemtrexed induced pneumonitis is a very rarely reported form of drug-induced lung disease occuring as a result of the drug pemtrexed (Alimta) which is used in treatment of malignant mesothelioma and non-small cell lung cancer (NSCLC).

Only limited literature has been published with most cases presenting as an acute pneumonitis (onset ranging between a few days to 4 weeks from dose) and reported to occur after 1-5 cycles . Variable outcomes have been reported.