sacral agenesis

Sacral agenesis (also considered as part of the caudal regression syndrome) is a rare and severe sacral developmental abnormality.

Epidemiology

In normal pregnancy, the incidence is between 0.005 and 0.1%. However, in fetuses with diabetic mothers, the incidence rises to 0.2%. Of those with the condition, 16-20% have diabetic mothers.

Pathology

Associations

• increased frequency of spinal dysraphism.
• Currarino triad

Classification

Sacral agenesis can be categorized into four types:

• type I: unilateral agenesis localized to sacrum or coccyx
• type II: partial agenesis with bilateral defects; the iliac bone articulates with S1, but the distal sacral elements fail to develop
• type III: total sacral agenesis; iliac bones articulate with the lowest lumbar element
• type IV: total sacral agenesis; iliac bones fuse posteriorly

See also 

• caudal regression syndrome

Siehe auch:

• caudal regression syndrome
• ASP-Assoziation
• Dysrhaphie

und weiter:

• caudal dysplasia sequence