Sclerodactyly

Sclerodactyly refers to fibrotic tightening and thickening of the skin, with atrophy of the soft tissues, of fingers and toes.

Pathology

Etiology

• scleroderma: seen in ~25% 
• CREST syndrome: seen in ~5%
• mixed connective tissue disease

History and etymology

Sclerodactyly is derived from the Greek skleros (hard) and dactyly (digit).

Differential diagnosis

• nephrogenic fibrosing dermopathy
• scleroedema adultorum of Buschke (scleroedema diabeticorum)
• scleromyxedema