transient global amnesia

Transient global amnesia (TGA) is a clinical syndrome with no clear etiology identified. Most symptoms are transient and resolve within a few hours.

Epidemiology

Most common in patients of older age (50-70 years old).

Clinical presentation

Anterograde and partial retrograde amnesia lasting less than 24 hours without any other neurological or congestive symptoms. Most cases show complete resolution of symptoms within a few hours from onset of symptoms.

Pathology

Several hypotheses (e.g. epileptic phenomena, stroke, focal ischemia) have been proposed with no consensus on the exact mechanism .

Radiographic features

Brain CT scan and conventional sequences of MRI brain show no abnormalities.

MRI

Prospective and retrospective studies based on a small number of TGA patients can detect small punctate regions of abnormally restricted diffusion on DWI/ADC sequences in the CA1 area of the hippocampus (lateral edge of the hippocampal gyrus abutting the temporal horn). These lesions can be bilateral and even multifocal .

Treatment and prognosis

No treatment is required and the condition tends to not recur .

Siehe auch:

• Diffusionsrestriktion Hippocampus
• hippocampale Sulcusreste
• transient global amnesia diffusion restriction

und weiter:

• Hippocampus
• Transposition der großen Arterien
• Diffusionsrestriktion bei TGA
• TGA