van der Woude syndrome

van der Woude syndrome (VWS) is characterized by the association of congenital lower lip fistulae/pits with cleft lip and/or palate.

It is one of the most common clefting syndromes in humans and affected individuals have a high prevalence of hypodontia.

It carries an autosomal dominant inheritance. Although caused by a single gene mutation, Van der Woude syndrome has variable phenotypic expression.

Assoziationen und Differentialdiagnosen zu van der Woude syndrome (VWS):

Lippen-Kiefer-Gaumen-Spalte