nicht verwechseln mit: Wermer-Syndrom

Werner syndrome is a progeroid rare autosomal recessive condition attributed to chromosome 8. It should not to be confused with similarly sounding Wermer syndrome.


Werner syndrome is characterized by

  • premature senescence
  • cataracts
  • short stature
  • scleroderma-like skin changes such as hyperkeratotic skin, soft tissue calcification
  • endocrine abnormalities such diabetes mellitus and hypogonadism

The syndrome also carries an increased risk of malignancy (particularly sarcoma formation ).

Radiographic features

A general manifestation is valvular, soft tissue and/or arterial calcification from premature atherosclerosis. Musculoskeletal manifestations includes:


First described by Otto Werner, German scientist, in 1904.

Siehe auch:
und weiter: