bilateral megalencephaly
Bilateral megalencephaly refers to megalencephaly affecting both cerebral hemispheres.
Pathology
Associations
- achondroplasia
- acromegaly
- Alexander disease
- Canavan disease
- mucopolysaccharidoses
- neurofibromatosis type 1 (NF1)
- Proteus syndrome
- Tay-Sachs disease
- tuberous sclerosis (TS)
- vacuolating megalencephalic leukoencephalopathy (van der Knapp disease)
Radiographic features
Antenatal ultrasound
The diagnosis may be suggested when the HC:AC ratio is above the 99percentile without evidence of IUGR (i.e low AC), fetal hydrocephalus or an intracranial mass.
See also
Siehe auch:
Assoziationen und Differentialdiagnosen zu bilateral megalencephaly:
