Honeycombing is a CT imaging descriptor referring to clustered cystic air spaces (between 3-10 mm in diameter, but occasionally as large as 2.5 cm) that are usually subpleural, peripheral and basal in distribution. They can be subdivided into:
Honeycombing consists of enlarged air spaces with thick fibrotic walls lined by bronchiolar epithelium and often filled with mucin and inflammatory cells .
History and etymology
The term “honeycomb lung” is thought to have originated in the 19century in Germany and is thought to have first appeared in 1949 in a study by N Oswald and T Parkinson .