multicystic encephalomalacia

Multicystic encephalomalacia corresponds to a variant of encephalomalacia commonly seen in neonates in which numerous loculated lacy pseudocysts within the white matter and cortex are present as a result of an extensive brain insult.

Pathology

It is a common feature observed in the neonatal hypoxic-ischemic encephalopathy in a term neonate, including as a sequela of severe postnatal non-accidental head injury .

Radiographic features

Multicystic encephalomalacia can be appreciated on both CT and MRI. Classic features generally include:

  • multiple cysts of varying size and shape located bilaterally within the cerebral white matter and inner layers of the cortex
  • relative sparing infratentorially, including of the cerebellum and spinal cord, except from Wallerian degeneration of the corticospinal tracts
  • relative sparing of some supratentorial structures including the basal ganglia, inferior temporal lobes, and orbital surfaces of the frontal lobes
  • ex vacuo dilatation of the lateral ventricles with intact ventricular walls

In cases secondary to severe postnatal non-accidental head injury, there may be evidence of chronic subdural hemorrhage, among other traumatic injuries.

See also

Siehe auch:
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