Leptospirose

Leptospirosis results from infection by the zoonotic Leptospira spp. The condition can have multiorgan manifestations. Commonly affected organs include:

Terminology

The term Weil disease (or Weil syndrome) is reserved for a severe form of leptospirosis in which there is jaundice, often also accompanied by: uremia, anemia, a bleeding tendency, fever, and delirium. Other names used for this condition include: Fiedler disease, icterohemorrhagic leptospirosis, and infectious or leptospiral jaundice.

Pathology

Typically occurs as a biphasic illness:

  • acute phase: last 4-9 days
  • asymptomatic period: 1-3 days
  • late phase: 1-3 days

History and etymology

It was first described by Adolf Weil, a German physician (1848-1916) .

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