Bickerstaff-Enzephalitis
Bickerstaff encephalitis is a rare immune-mediated condition believed to be one of a number of conditions sharing a similar immunological mechanism, and collectively termed anti-GQ1b IgG antibody syndrome.
Clinical presentation
Bickerstaff encephalitis is often seen following varicella zoster virus and cytomegalovirus infections .
Patients typically present acutely with cerebellar ataxia and external ophthalmoplegia. They may also demonstrate drowsiness, hemisensory disturbance as well as brisk reflexes and extensor plantar response .
Radiographic features
MRI
It transiently involves the brainstem and basal ganglia and is characterized on MRI by regions of high T2 signal with little - if any - enhancement. Typically these regions also demonstrate some minor restricted diffusion .
Treatment and prognosis
Although symptoms are severe, the condition is usually self-limiting with a good prognosis .
History and etymology
Bickerstaff encephalitis was first described by Edwin Robert Bickerstaff (1920-2007), a renowned British neurologist .
Siehe auch:
Assoziationen und Differentialdiagnosen zu Bickerstaff-Enzephalitis:
