4D syndrome
4D syndrome is a term used to describe a manifestation of syndromic glucagonomas, a type of pancreatic endocrine tumor.
- D: dermatitis
- necrolytic migratory erythema - a widespread rash, tending to involve perioral and perigenital regions
- oral rashes (angular stomatitis, cheilitis)
- tend to resolve upon removal of the tumor
- D: mild diabetes mellitus
- D: deep vein thrombosis
- D: depression - may be related to severe chronic dermatosis
