angiocentric immunoproliferative lesion

Lymphomatoid granulomatosis, also known as angiocentric lymphoma or angiocentric immunoproliferative lesion, is a rare type of non-Hodgkin's lymphoma associated with Epstein-Barr virus infection.

Pathology

There is a recognized association with antecedent infection with the Epstein Barr virus (EBV).

It can affect a variety of organs:

  • lung involvement: ~80% of cases
  • skin (cutaneous) involvement: 33-50% 
  • CNS involvement: 20%

Radiographic features

Radiographic features are discussed separately:

History and etymology

It was initially described by Leibow et al. in 1972 .

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