asbestos body
An asbestos body is a histological finding in interstitial lung disease that is suggestive of significant occupational asbestos exposure. They are usually identified following a parenchymal lung biopsy .
Macrophage ingestion of the asbestos fibers triggers a fibrogenic response via the release of growth factors that promote collagen deposition by fibroblasts. The fibers become encased in iron-rich material derived from proteins such as ferritin and hemosiderin . They typically appear as brown nodules in the septum of the alveolus and may have a rod or dumbbell shape with multiple segmentations.
Asbestos bodies are just one type of ferruginous bodies that can be formed by iron encasement of inhaled inorganic dusts.
See also
Siehe auch:
und weiter:
Assoziationen und Differentialdiagnosen zu asbestos body:
