Bilateral frontoparietal polymicrogyria

Bilateral frontoparietal polymicrogyria (BFPP) is a rare genetic condition consisting of extensive bilateral perisylvian polymicrogyria.

As is the case with many areas of medicine transitioning from phenotypical to molecular/genetic definitions, it has been postulated what bilateral frontoparietal polymicrogyria may be on a continuum with other related conditions, in this case cobblestone lissencephaly .

Pathology

So far (as of 2015) only a single gene association has been identified; GPR56 gene located on chromosome 16q12.2–21 . It is inherited as an autosomal recessive disorder .

Radiographic features

The radiographic appearances are discussed in the article on polymicrogyria.

Siehe auch:

• Polymikrogyrie
• bifrontal and bilateral parasagittal parieto-occipital polymicrogyria