Clinically amyopathic dermatomyositis

Amyopathic dermatomyositis (ADM) is recognized as a distinct subtype of dermatomyositis where there is a typical skin rash of classic dermatomyosiytis but without muscle involvement.

Sub types

This form may be further divided into

• anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive clinically amyopathic dermatomyositis
• anti-melanoma differentiation-associated gene 5 (MDA5) antibody-negative clinically amyopathic dermatomyositis

Associations

• interstitial lung disease: 
• malignancies:
  • according to one study, malignancy of the genitourinary organs (most common), aerorespiratory organs and breast were the most commonly observed solid organ tumors.