congenital oral granular cell myoblastoma

Ossifying
fibrous epulis as an IgG4-related disease of the oral cavity: a case report and literature review. Patient status. A Oral findings at first examination: a pedunculated tumour (approximately 65 × 45 mm) is present in the left lower gingiva. The base is localised in the alveolar region, and the surface is granulomatous, elastic-hard with partial ulcerations, and haemorrhagic. The tongue is displaced rightward by the tumour (arrow). B Panoramic radiography revealed compressive bone resorption in the region corresponding to the tumour (arrow). C MRI images: (a) Contrast T1-Gd-MRI revealed significant contrast throughout the tumour, more pronounced along the margin; (b) T2-STIR-MRI revealed a high intensity at the margin and moderate intensity in the inner region. D Imaging of the submandibular lymph node: (a) in the contrast-enhanced CT image, contrast-enhanced swollen lymph nodes (arrows) are present in the bilateral submandibular regions. Both the right (b) and left (c) submandibular lymph nodes are soft, with smooth margins on cervical echo. The hilum of the lymph node is clear, but an increase in blood flow is noted in the hilum region. T1-Gd-MRI: T1-weighted gadolinium-enhanced magnetic resonance imaging, T2-STIR: T2-weighted short inversion recovery
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Multiple
congenital granular cell epulis in a female newborn: a case report. (a,b) Multiple masses present in the anterior maxillary and mandibular alveolar ridge in a 4-day-old female newborn with congenital granular cell epulis.
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Spontaneous
regression of congenital epulis: a case report and review of the literature. Lesion at age three weeks.
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A congenital granular cell myoblastoma (also known as congenital epulis) is a very rare benign tumor which classically presents in the fetal-neonatal population.

Epidemiology

It occurs almost exclusively in females when it presents in the fetal-neonatal population although no such predilection occur when it rarely presents in older children.

Pathology

It is thought to occur as a result of excessive estrogen production from the fetal ovaries under HCG stimulation.

The histogenesis is uncertain, and proposed cells of origin include odontogenic epithelium, undifferentiated mesenchymal cells, pericytes, fibroblasts, smooth muscle cells, nerve-related cells, and histiocytes.

Location

It most commonly occurs along the alveolar ridge of the maxilla although less commonly, it can also occur in relation to the mandible.

Radiographic features

Antenatal ultrasound

Rarely a congenital epulis may be detected on antenatal ultrasound as an intra-oral mass. Color and power Doppler ultrasound examination may show marked blood flow within the tumor .

Differential diagnosis

General considerations include

Siehe auch:
und weiter:
Assoziationen und Differentialdiagnosen zu epulis:
Teratom des
Pharynx
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