Endocrine venous sampling

Endocrine venous sampling is a set of similar interventional techniques proposed for the specific diagnosis of some endocrine disorders such as:

  • inferior petrosal sinus sampling
  • selective venous sampling for primary hyperparathyroidism
    • preoperative localization of functioning parathyroid adenoma which cannot be localized by imaging
  • arterial stimulation and selective venous sampling for pancreatic endocrine tumors
    • used for preoperative localization of pancreatic endocrine tumors (gastrinoma, insulinoma, VIPoma, glucagonoma, somatostatinoma and pancreatic polypeptide-producing tumor)
  • adrenal venous sampling
    • used for identification of primary aldosteronism (Conn syndrome or bilateral idiopathic adrenal hyperplasia). 
  • ovarian venous sampling
    • used to stablish the source of excessive androgen production in women when imaging studies are not revealing

Renal vein sampling (renin sampling) was used for the determination of renal artery stenosis as cause of hypertension (renovascular hypertension), now infrequently performed .