Epithelioid hemangioendothelioma (EHE) is a rare relatively low grade vascular tumor. It occurs around medium to large venous structures.
It consists of rounded or slightly spindle-shaped eosinophilic endothelial (epitheloid) cells with rounded nuclei and prominent cytoplasmic vacuolisation.
- factor VII-associated antigen
It can occur in a number of sites
- liver: hepatic epithelioid hemangioendothelioma
- lung: pulmonary epithelioid hemangioendothelioma
- limbs: skin and soft tissues
Please refer to individual location-specific entities for specific features.
History and etymology
It was initially described by SW Weiss and FM Enzinger in 1982 .
- infantiles Leberhämangioendotheliom
- Malignes epitheloides Hämangioendotheliom
- pulmonary epithelioid haemangioendothelioma
- epitheloides Hämangioendotheliom der Leber