human herpesvirus 6 encephalitis
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Encephalitis
in bone marrow transplant patient. Axial FLAIR image demonstrates symmetric high T2 signal and oedema in the mesial temporal lobes bilaterally.
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Encephalitis
in bone marrow transplant patient. Repeat MRI 3 weeks after therapy shows partial resolution of the mesial temporal lobe high T2 signal, which correlated with clinical recovery.
Human herpesvirus 6 (HHV-6) encephalitis is a rare CNS infection due to human herpesvirus 6 reactivation in immunosuppressed patients, especially in those following a hematopoietic cell transplant who develop a characteristic limbic encephalitis syndrome with MRI signal intensity abnormalities of the mesial temporal lobe .
Studies have been conducted to investigate possible associations of HHV-6 with mesial temporal lobe epilepsy (mesial temporal sclerosis) and multiple sclerosis (MS) .
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