IgG4-related lung disease

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IgG4-related lung disease is a recently described condition. It may occur with or without systemic involvement. It is considered part of the spectrum of IgG4-related disease.

Radiographic features

CT

On HRCT of the chest, it may be categorized into four major subtypes :

  • solid nodular subtype
  • round-shaped ground-glass opacities: showing multiple rounded ground glass opacities
  • alveolar interstitial subtype: showing honeycombing, bronchiectasis and diffuse ground glass opacity
  • bronchovascular subtype: showing thickening of bronchovascular bundles and interlobular septa