Immune checkpoint inhibitor therapy

Immune checkpoint inhibitor therapy is a relatively new treatment for certain cancers which result in immune system-mediated destruction of tumor cells.

Immune checkpoint inhibitors act through a unique mechanism of action when compared with those of conventional chemotherapeutic agents. They target cell surface receptors:

  • cytotoxic T-lymphocyte antigen-4
  • programmed cell death protein 1
  • programmed cell death ligand 1 (PD-L1)

Complications

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