An incidentaloma is a radiological neologism to denote a lesion found incidentally and of dubious clinical significance. Although it can refer to any incidental lesion (e.g. pituitary , thyroid ), it is most often used to denote an incidental adrenal lesion, which is commonly an adrenal adenoma . Colloquially, some radiologists use the term interchangeably with adrenal adenoma, although clearly its use in a report would be confusing, and should be avoided. Most incidentalomas are asymptomatic.

If an adrenal adenoma is found incidentally, please refer to the Management of incidental adrenal masses: American College of Radiology white paper.

The likelihood of an incidental adrenal lesion being malignant is most strongly determined by the presence or absence of a malignancy elsewhere. In cases where a malignancy is present, up to 27% of incidental adrenal lesions represent adrenal metastases .

History and etymology

The word 'incidentaloma' first appears in the literature in 1982 in a paper by Glenn W Geelhoed (fl. 2019), a surgeon, and Edward M Druy (fl. 2019), a radiologist .

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