Intramembranous ossification
Intramembranous ossification describes the process of ossification from mesenchymal cells (stem cells) without a cartilaginous template and is involved in the healing process of fractures. The stages of intramembranous ossification osteogenesis are as follows:
- mesenchymal cells differentiate into osteoblasts
- osteoblasts deposit matrix which becomes mineralized
- immature woven trabeculae (primary spongiosa) is deposited
- primary spongiosa is replaced by secondary bone
- bone marrow formation
- primary cortical bone
Gross anatomy
Seen in the formation of:
