Meigs syndrome

Meigs syndrome is defined as the presence of ascites and pleural effusion in association with a benign, usually solid ovarian tumor. In the vast majority (80-90%) of cases, the primary tumor is an ovarian fibroma. Other primary tumors include:


The pathophysiology of ascites in Meigs syndrome is speculative. It was initially suggested that irritation of the peritoneal surfaces by a hard, solid ovarian tumor could stimulate peritoneal fluid production. The pathophysiology of the pleural effusion is also speculative with some suggesting ascitic fluid being transferred via trans-diaphragmatic lymphatic channels into the pleural space.


The pleural fluid tends to be right sided in a majority (~60-70%) of cases.

Treatment and prognosis

The condition is benign and the ascites and pleural effusion resolve after resection of the primary pelvic tumor.

History and etymology

Named after Joe Vincent Meigs (1892-1963), an American (US) obstetrician and gynecologist  .

Differential diagnosis

General considerations include:

Siehe auch:
und weiter: