METAVIR score

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The METAVIR​ scoring system is a system used to assess the extent of inflammation and fibrosis by histopathological evaluation in a liver biopsy of patients with hepatitis C. The grade indicates the activity or degree of inflammation while the stage represents the amount of fibrosis or scarring.

Activity grade
  • A0: no activity
  • A1: mild activity
  • A2: moderate activity
  • A3: severe activity
Fibrosis stage
  • F0: no fibrosis
  • F1: portal fibrosis without septa
  • F2: portal fibrosis with few septa
  • F3: numerous septa without cirrhosis
  • F4: cirrhosis

See also